NOTE about test result:  The results from this batch show purity at 98.45%, under our 99% standard cutoff. However, all previous results from same batch showed 99% plus. This disparity is likely due to the excipient formulation and is an anomaly. Nonetheless, the price has been adjusted to reflect this. 

KPV – Alpha melanocyte-stimulating hormone (α-MSH), also known as melanotropin, is an endogenous peptide hormone consisting of 13 amino acids. This hormone is considered to play a role in metabolic functions and other biological processes. Researchers isolated a fragment of this protein hormone, identifying its biological potential, and naming it KPV peptide. KPV comprises three amino acids: lysine, proline, and valine.⁽¹⁾ This peptide is a C-terminal fragment of the α-MSH protein hormone and is considered the primary amino acid sequence responsible for its action.

In 1989, a study explored the isolation and biological potential of the KPV tripeptide. Upon identifying the COOH terminal peptide in the α-MSH hormone as the primary amino acid messenger sequence, scientists conducted preliminary research to determine if KPV might prevent excessive vasopermeability and swelling of blood vessels. Researchers isolated the KPV peptide and presented it to the experimental mice to assess its potential to mitigate ear swelling. The study concluded that the isolated fragment appeared to inhibit swelling. KPV’s potential anti-inflammatory action may be induced by inactivating inflammatory pathways and possibly inhibiting the synthesis and release of pro-inflammatory cytokines in intestinal and immune cells.

Key Benefits of KPV Research:

• Anti-inflammatory properties

• Wound healing support

• Gut health and IBD research

• Immune modulation

• Non-toxic and well-tolerated

• Naturally occurring

• Neurological potential

• Topical and systemic applications

Chemical Structure