Mazdutide
Mazdutide
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READ THIS PLEASE: These Statements Have Not Been Evaluated By The Food And Drug Administration. This Product Is Not Intended To Diagnose, Treat, Cure Or Prevent Any Disease.
Mazdutide (also known by its development code IBI362) is an investigational research compound being studied for its potential therapeutic applications in metabolic disorders, including obesity and type 2 diabetes. It is a dual agonist that targets both the glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR). These receptors are crucial in regulating energy balance, glucose metabolism, and lipid homeostasis.
Mechanism of Action
Mazdutide’s dual activity:
- GLP-1R Agonism: Enhances glucose-dependent insulin secretion, delays gastric emptying, and promotes satiety, contributing to improved glycemic control and weight loss.
- GCGR Agonism: Increases energy expenditure and mobilizes lipid stores by promoting hepatic glucose output and lipid oxidation.
Potential Benefits
Preclinical and early clinical studies suggest mazdutide has the potential to:
- Reduce body weight through appetite suppression and increased energy expenditure.
- Improve glycemic control by enhancing insulin sensitivity and reducing hepatic glucose production.
- Address lipid metabolism abnormalities in conditions such as non-alcoholic fatty liver disease (NAFLD).
Current Status
Mazdutide is being developed by Innovent Biologics and has progressed through Phase 1 and Phase 2 clinical trials. Early results indicate promising efficacy and tolerability, though further studies are required to fully understand its safety profile and long-term effects.
Research Applications
Mazdutide is a valuable tool for exploring the interplay between GLP-1 and glucagon signaling pathways in metabolic regulation. It also holds potential for advancing treatments for complex metabolic diseases.
Chemical Structure
Looking for test results? Click the link below.
Mazdutide - TEST RESULTS (Certifcate of Analysis)
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• Products sold on our website are meant for scientific research purposes only, designed for in vitro testing and lab experimentation exclusively. These products are not intended to be used as foods, drugs or cosmetics, any sort of bodily introduction of the products into humans or animals is strictly prohibited. They must also not be misbranded, misused, or mislabeled, or used for anything other than research and scientific investigation.
• All the products you see on the website are being sold in a lyophilized powder state (freeze-dried), in a sealed sterile vial; and should be reconstituted.
• The product’s label clearly states the amount of product a vial contains; some products are offered in different variations.
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• Though we make sure packaging, label, seals and writing does not differ from the product photos you see on our website, there is a chance for a minimal deviation.